The new store in Yiewsleyhas received 2500 applications for 200 jobs.
In a sign that the economy is biting hard, the rush of applications is taken as confirmation of reports that recent figures have shown unemployment in Hillingdon has risen by a third in the past year.
Gail Roberts, retail recruitment manager at Morrisons told the Uxbridge Gazette: "We have had an amazing response to the recruitment drive and are really positive that we will build up a team that can deliver great service to the people of Yiewsley."